Sepsis results from an infection which may arise in the lungs, urinary tract, skin, abdomen or other part of the body.
The commonest causes of sepsis are respiratory infections, abdominal infections (such as can arise from a perforated bowel or from kidney or gall stones) and urinary infections. Sepsis may occur in patients both in the community and those already being treated in hospital . Sepsis can occur due to an infection contracted after surgery.
Many different types of microbes, including bacteria, fungi and viruses, can cause sepsis but bacteria are the most common cause. Severe cases often result from a body-wide infection that spreads through the bloodstream, but sepsis can also stem from a localized infection.