Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: A before and after cohort study

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Venkatesh, Balasubramanian et al.
The Lancet Regional Health – Western Pacific, Volume 18

Sepsis bundles, promulgated by Surviving Sepsis Campaign have not been widely adopted because of variability in sepsis identification strategies, implementation challenges, concerns about excess antimicrobial use, and limited evidence of benefit.

This research found that implementing 1-hour and 3-hour sepsis bundles for patients presenting with bacteraemia resulted in improved bundle compliance and a reduced need for ICU admission without adversely influencing antimicrobial prescription.

Read the full paper on the study here Impact of 1hr and 3hr sepsis bundles